Week 5: Reproducibility of scientific findings, Part 2

This is part 2 of the lesson on scientific reproducibility. Links to other lessons are the end of this post. How can you trust the scientific information you read? Continue reading Week 5: Reproducibility of scientific findings, Part 2

Week 5: Reproducibility of scientific findings, Part 1

Happy New Year! This is the 5th lesson in a 7-lesson course and it is first being posted in 2019. We hope students continue to find it useful any time!

If you have been listenting to current science news, you might have heard the terms reproducibility and replication, particularly in the context of whether we should trust scientific results.

The video in this lesson is a very measured and truthful look at science reproducibility (Thanks TedEd! https://ed.ted.com/lessons/is-there-a-reproducibility-crisis-in-science-matt-anticole,CC BY-NC-ND 4.0). Continue reading Week 5: Reproducibility of scientific findings, Part 1

Comparing conflicting data with ReFigure

Conflicting literature is a fact of life in academic research.  Labs in conflicted fields undoubtedly have opinions about which experiments and publications are favored and why.  However, a public platform for comparison does not exist, meaning that all the insights from discussions that occur between colleagues and at lab meetings are not distributed to the scientific community at large.  ReFigure has given me a mechanism to conduct comparisons between publications, helping to discern the subtle differences in expression systems, experimental setup, or cloning that might explain conflicting results.  Not only can I use ReFigure to organize my own thoughts so as to progress my research, it allows me to organize these ideas publically to help others in my field. I invite you to read further and view my ReFigure.

Continue reading Comparing conflicting data with ReFigure

Antibody reproducibility with ReFigure, a collaboration with Antybuddy

We are pleased to announce the start of a collaboration with Antybuddy,  an antibody and protein review platform for crowdsourced independent reviews. These reviews are from bench researchers who have experimented with the antibody. No longer do you have to trust the manufacturer that the antibody works. View existing reviews on Antybuddy.com or contribute your own. As an incentive, Antybuddy has sweepstakes for coupons from antibody manufacturers.

In collaboration with Giancarlo Barone, the founder of Antybuddy, we wanted readers to have access to the published reports for antibodies and to be able to compare their performance across published reports and the independent reviews. Continue reading Antibody reproducibility with ReFigure, a collaboration with Antybuddy